Information for Medical Professionals

Personalised Prostate Cancer Prevention is an up-to-date solution aimed at minimising the potential impact of prostate cancer by tailoring it to a man’s genetic risk level.

It begins with polygenic risk score testing (AntePC test), as polygenic risk score is the strongest independent risk factor for prostate cancer. Based on the test results, men receive personalised medical plans for screening and prevention.

This guidance includes when and how to initiate prostate cancer screening and other effective strategies to reduce personal risks. The service also includes a family history questionnaire for breast cancer, based on which it is determined whether the man requires additional testing for rare monogenic pathogenic variants (in genes such as BRCA1, BRCA2, etc.).

Armed with scientifically backed and well-documented medical advice, men can take preventive measures within their local healthcare system to protect their health proactively.

Recommended for men aged 40 and above.

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The service includes:

  • Polygenic risk assessment of prostate cancer (AntePC test) combined with age, population background and ethnic information.
  • Medical plans with clinical recommendations based on personal polygenic risk level for prostate cancer prevention and early detection.
  • Family cancer history questionnaire to assess the need for monogenic pathogenic variant (MPV) testing; if indicated, recommendations for a medical geneticist consultation and MPV testing. Based on family history criteria for prostate cancer, men can also undergo MPV testing through their GP within the NHS system. The current service determines the need for this.
  • Following possibilities to implement prostate cancer prevention and control according to personalised medical plans (relevant information is provided in these personalised medical plans).
  • Optional: possibilities for additional verbal counselling and consultations with medical professionals.
Read the scientific background
Prevent
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